Therefore, it should be no surprise that the massive money printing has caused massive asset price inflation (not evenly) since 2009. This can be seen in the following charts showing the correlation of the US Fed balance sheet and the US share market (S&P500).
Now, it is a historical fact that any time since 1880, that Shiller's CAPE ratio got anywhere near the level indicated above (32.11), this was followed by a major crash in the US share market (see chart immediately below for relationship between high CAPEa and share market crashes). This is an ominous warning for index-like investors in US shares. (There are some other asset sector and markets which are also in asset price bubbles as well of course). Investors ignoring this sort of warning do so at their own peril.
But when will the US share market crash? Fundamental measures like Shiller's CAPE ratio, warning of such an event in the future, but they do not tell you when. However, there is a reasonable school of thought that suggests as follows. If it was the massive money printing in by developed world central banks (seen in growing central bank balance sheets) that caused the US share market bubble, then "surely" as that balance sheet shrinks (or developed world central bank balance sheets more broadly), then so will the US share market bubble. Personally I think this is quite likely to be the case. And so does Gavekal https://web.gavekal.com/, a highly regarded research house based in Hong Kong. https://www.puzzlefinancialadvice.com/single-post/2017/10/18/Recession-risk-warning-for-2019
Another factor which seems likely to tell us something about the timing, us the US Fed cash rate. Historically, rising US cash rates have been highly correlated with financial crises. Note: Over the last few days, the US Fed has raised its cash rates by another 0.25%, and expects to raise US cash rates another 2 times before year end. https://fred.stlouisfed.org/series/FEDFUNDShttps://fred.stlouisfed.org/series/TB3MS